Do not mix mesnex injection with epirubicin, cyclophosphamide, cisplatin, carboplatin, and nitrogen mustard. Highlights of prescribing information palmarplantar. The benzyl alcohol contained in mesnex injection vials can reduce the stability of ifosfamide. Cytoxan cyclophosphamide for injection, usp cytoxan tablets cyclophosphamide tablets, usp description cytoxan cyclophosphamide for injection, usp is a sterile white powder containing cyclophosphamide mono hydrate. Cyclophosphamide is well absorbed after oral administration with a bioavailability greater than 75%. See important safety including boxed warnings for more information. Dosing and administration brochure please see pages 2427 and accompanying full prescribing information, including boxed warnings and. It is supplied as a nonpyrogenic, sterile lyophilized powder for intravenous, intracavitary or intravesical administration, containing 15 mg and 30 mg of thiotepa.
Cyclophosphamide is a synthetic antineoplastic drug chemically related to the nitrogen mustards. Each ml of the sterile solution contains 20 mg of plerixafor. Cytoxan cyclophosphamide for injection, usp is a sterile white powder containing cyclophosphamide monohydrate. Vectibix is not indicated for the treatment of patients with colorectal cancer that harbor somatic ras mutations in exon 2 codons 12 and, exon 3 codons 59 and 61, and exon 4 codons 117 and 146 of either kras or nras and hereafter is referred to as. Package insert thiotepa for injection, usp description thiotepa for injection is an ethyleniminetype compound. To prepare reduced doses for patients with baseline crcl less than or equal to 60 mlmin, withdraw the. Sections or subsections omitted from the full prescribing information are not listed.
Cyclophosphamide for injection, usp is a sterile white powder containing cyclophosphamide monohydrate. It is a cardioprotective agent for use in conjunction with doxorubicin. Mesnex is indicated as a prophylactic agent in reducing. Doxorubicin hydrochloride for injection, usp patient. Afinitor is a prescription medicine used to treat adults with a type of cancer known as neuroendocrine tumor net of the stomach and intestine gastrointestinal or lung that has progressed and cannot be treated with surgery. Abraxane is indicated for the firstline treatment of locally advanced or metastatic nonsmall cell lung cancer, in combination with carboplatin, in patients who are not candidates for curative surgery or radiation therapy. Highlights of prescribing information these highlights do not include all the information needed to use femara safely and effectively. Desferal is not indicated for the treatment of primary hemochromatosis, since phlebotomy is the method of choice for removing excess iron in this disorder. Mozobil plerixafor injection is a sterile, preservativefree, clear, colorless to paleyellow, isotonic solution for subcutaneous injection. Although women taking cyclophosphamide can stop having periods, they can still become pregnant, so an effective form of birth control to prevent pregnancy should be used while taking this medication since cyclophosphamide can cause fetal harm. Patients in these studies received standard doses of doxorubicin and standard or escalated doses of cyclophosphamide ac adjuvant chemotherapy and were followed for 61,810 patient years. Cyclophosphamide for injection, usp rx only description cyclophosphamide for injection, usp is a sterile white powder containing cyclophosphamide monohydrate. Mesnex is not indicated to reduce the risk of hematuria due to other pathological conditions such as thrombocytopenia.
Cytarabine injection, an antineoplastic, is a sterile solution of cytarabine for intravenous and subcutaneous use which contains no preservative and is available in 20 mgml mg50 ml pharmacy bulk package. Cytoxan tablets cyclophosphamide tablets, usp are for oral use and contain 25 mg or 50 mg cyclophosphamide. Mesnex is a cytoprotective agent indicated as a prophylactic agent in reducing the incidence of ifosfamideinduced hemorrhagic cystitis. Velcade is administered twice weekly for two weeks days 1, 4, 8, and 11 followed by a ten day rest period on days 12 to 21. Anthracyclines including doxorubicin should not be administered in combination with other cardiotoxic agents unless the patients cardiac function is closely monitored. Cyclophosphamide tablets, usp are for oral use and contain 25 mg or 50 mg cyclophosphamide anhydrous. Cyclophosphamide can cause infertility in both men and women. Other regimens include 10 mg per kg to 15 mg per kg given every 7 to 10 days or 3 mg per kg to 5 mg per kg twice weekly.
Thiotepa is a synthetic product with antitumor activity. Cytoxan fda prescribing information, side effects and uses. Tablets containing sorafenib tosylate 274 mg equivalent to 200 mg of sorafenib. Cyclophosphamide tablets, usp description cyclophosphamide for injection, usp is a sterile white powder containing cyclophosphamide monohydrate.
Velcade is administered first followed by rituximab. Hepatotoxicity see full prescribing information for complete boxed warning. Rheumatoid arthritis ra rituxan rituximab in combination with methotrexate is indicated for the treatment of adult. Highlights of prescribing information these highlights do not include all the information needed to use baraclude safely and effectively. Initial course for patients with no hematologic deficiency. Among 4483 such patients who received conventional doses of ac, 11 cases of aml or mds were identified, for an incidence of 0.
Cytoxan cyclophosphamide for injection, usp cytoxan. The unchanged drug has an elimination halflife of 3 to 12 hours. Cyclophosphamide is a synthetic antineoplastic drug. Highlights of prescribing information these highlights do not include all the information needed to use dacogensafely and effectively. Desferal is contraindicated in patients with severe renal disease or anuria, since the drug and the iron. Cytoxan tablets cyclophosphamide tablets, usp are for oral use and contain 25 mg or 50 mg cyclophosphamide anhydrous. In combination with fludarabine and cyclophosphamide fc, for the treatment of patients with previously untreated and previously treated cd20positive cll.
Contraindications known hypersensitivity to the active substance. See 17 for patient counseling information and fdaapproved patient labeling. These highlights do not include all the information needed to use halaven safely and effectively. Rituxan rituximab is indicated, in combination with fludarabine and cyclophosphamide fc, for the treatment of patients with previously untreated and previously treated cd20positive cll. Inactive ingredients in cyclophosphamide tablets are. Refer to everolimus prescribing information for recommended everolimus dosing information.
Nexavar tablets are round, biconvex, red filmcoated tablets, debossed with the bayer cross on one side and 200 on the other side. Cyclophosphamide is a white crystalline powder with the molecular formula c 7 h 15 cl 2 n 2 o 2 p h 2 o and a molecular weight of 279. Highlights of prescribing information these highlights do not include all the information needed to use sutent safely and effectively. Prophylactic gcsf may be used to mitigate the risk of hematological toxicities see dosage and administration 2. Ifosfamide and mesnex may be mixed in the same bag provided the final concentration of ifosfamide does not exceed 50 mgml. The chemical name for cyclophosphamide is 2bis2chloroethylaminotetrahydro2h1,3,2oxazaphosphorine 2oxide monohydrate. Cyclophosphamide does not contain any antimicrobial preservative and thus care must be taken to assure the sterility of prepared solutions. Highlights of prescribing information these highlights do not include all the information needed to use votrient safely and effectively. Four preoperative cycles of dosedense doxorubicin and cyclophosphamide ddac alone followed by 4 preoperative cycles of perjeta in combination with paclitaxel and trastuzumab or trastuzumab hyaluronidaseoysk as given in berenice following surgery, patients should continue to receive perjeta and trastuzumab or. It is eliminated primarily in the form of metabolites, but from 5 to 25% of the dose is excreted in urine as unchanged drug.
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